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None of these are deal-breakers on their own
12 Adipose tissue expansion increases leptin levels, which regulate appetite, energy expenditure, and glucose and lipid metabolism via hypothalamic signaling

14-year rule, the EU cap is 15 years of total exclusivity from the date of first authorization

This is where the GLP-1 or semaglutide drugs come into play

Whether this imbalance is optimal and enhances the efficacy of tirzepatide remains to be determined

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