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[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Luo J, Yang H, Song BL
During clinical trials, people receiving Zepbound lost up to nearly 21% of their starting body weight over 72 weeks (about 16.5 months)
Human data are often associative rather than interventional, assays lack standardization, and receptor mechanisms may be incomplete or contested
The decision to continue or discontinue GLP-1 therapy should be made collaboratively with your healthcare team, weighing metabolic benefits against biliary symptom risk
If lightheadedness, excessive fatigue, or nausea occurs during exercise, reduce intensity and ensure adequate pre-workout nutrition
Recent mechanistic papers also highlight cardiovascular, renal and neuroprotective actions
