glp 1 brain GLP-1 receptor biology: structure, signaling, and distribution Read "Examining Glucagon-Like Peptide-1 Receptor
Description
The intriguing oxyntomodulin (OXM), a peptide generated from proglucagon that is expressed in both the brain and the gut, may bind to the GLP-1R with a low affinity, allowing it to regulate hunger [26]

In the 1960s and 70s, scientists were puzzled by the observation that oral glucose caused a much greater insulin response than intravenous glucose

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Lancet 2009;373:473481

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