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GLP-1 analogs (exendin-4) can also improve hepatic steatosis [35] in ob/ob mice both in vivo and in vitro [36]

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Novo has since launched a broad late-stage program for CagriSema, including the Phase III trials REDEFINE 1, which is assessing its efficacy as a weight loss therapy, and REDEFINE 2, designed to include type 2 diabetes patients with excess body weight

Therefore, GLP-1 therapies dont replace other medications but instead complement them within the overall strategy

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The timeline for results from GLP-1 injections can vary depending on individual factors, but many patients begin noticing a reduction in appetite and modest weight loss within the first few weeks of starting therapy