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Abnormal (dysbiotic) gut microbiota could account for leaky gut and inflammation in older adults (3, 9), since dysbiotic microbiota can produce metabolites that interact with the hosts intestinal epithelial cells to reduce epithelial barrier proteins like zonulin-1 ( Zo1 ), occludin ( Ocln ), and claudins, resulting in disrupted cell-to-cell connections, which compromises intestinal permeability (10, 11)

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These early drugs had to be injected daily and were mainly aimed at improving blood sugar control

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If you are still in the dose titration phase of Saxenda treatment, your doctor may consider this when prescribing antibiotics, as gastrointestinal side effects tend to be more pronounced during this period