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This is also when the positive effects of weight loss on body image and confidence begin to counterbalance negative neurochemical effects, creating the paradoxical experience many women describe

Effect of Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) on Weight Loss Following Bariatric Treatment

This delayed emptying contributes to prolonged feelings of fullness but can also cause nausea, bloating, and early satiety, particularly during the first few weeks of treatment or after dose escalation

Neither group included patients taking concomitant SU therapy

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Large clinical trials have not identified seizures as a safety concern with these medications