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This effect is also observed after specific activation of GLP-1R in the NAc and most likely those receptors located on medium spiny neurons that express the dopamine-D1 receptors or dopamine-D2 receptors (Zhang et al., 2020)
Pickert G, Neufert C, Leppkes M, Zheng Y, Wittkopf N, Warntjen M, et al
Mounjaro is approved for blood sugar control in adults with type 2 diabetes, and like Ozempic, it may be prescribed off-label for weight loss
doi:10.1111/j.1471-4159.2010.06731.x 115
Res.) to match the weight loss of GLP-1MK-801 ( n = 8 mice and n = 4 cages) or vehicle (isotonic saline, n = 8 mice and n = 3-4 cages) for 14 days
Batterham Rachel, L
