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In fact, before researchers recognized their powerful weight loss capabilities, these medications originally treated individuals with type 2 diabetes

This hypothalamus/hindbrain focused model of GLP-1 action, however, does not easily accommodate the recent findings showing that GLP-1R stimulation reduces food reward behavior (Dickson et al., 2012)

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Kong W, Deng B, Shen X, John C, Haag J, Sinha N, Lee D, Sun W, Chen S, Zhang H, Clontz A, Hursting SD, Zhou C, Bae-Jump V

Diabetologia 16:2530 Hu FB, Manson JE, Stampfer MJ et al (2001) Diet, lifestyle, and the risk of type 2 diabetes mellitus in women
