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The clinical trials showed steady weight loss progression through 68 weeks, with the most rapid loss occurring between weeks 8 and 32

312 Coleus forskohlii

doi: 10.1016/j.jsbmb.2007.04.004

Short-chain fatty acids (SCFAs) such as butyrate, a bacterial metabolite produced from dietary fibre, can directly trigger GLP-1 release by binding to the membrane receptor GPR43 (65)