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These results are very promising, but TRIUMPH-4 included people with knee osteoarthritis, so the results may not apply exactly to every person using retatrutide for weight loss

Youll also need to adjust your dosage depending on what dose of Mounjaro you were previously taking
[3] [4] Simultaneously, GLP-1 suppresses glucagon secretion, slows gastric emptying, and sends satiety signals to the brain, helping you feel fuller for longer
Work with your doctor to establish a monitoring schedule

These trials were conducted by Novo Nordisk, the manufacturer of Ozempic, Wegovy, and Rybelsus, and published in The New England Journal of Medicine and Nature Medicine
