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While laboratory findings and observational studies suggest potential benefits against the biological drivers of dementia, results from large clinical trials in people with established Alzheimers are still inconclusive

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Indices of insulin sensitivity and secretion from a standard liquid meal test in subjects with type 2 diabetes, impaired or normal fasting glucose

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Briefly, cells were labelled with 1 M BG-S-S-649, a cleavable SNAP-Surface probe, in full media for 30 minutes at 37C, washed with PBS and stimulated with vehicle or 100 nM exendin-4 in reverse time order for 30, 15, 10 and 5 minutes at 37C in full media