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For pharma companies, these advancements open new opportunities in formulation development, manufacturing partnerships, and global expansion

Lipase inhibitors such as alli or Xenical (orlistat) have been associated with rare liver injury and patients should be alert for signs of liver disease such as itching, yellow skin or eyes (jaundice), stomach pain, loss of appetite, pale or tar-colored stools, brown-colored urine (due to excess bilirubin in the urine)

Cinelli, M

Excess skin can cause pain when walking, lifting or exercising due to chafing and rubbing

According to the UK Summary of Product Characteristics (SmPC), nausea occurred in approximately 1221% of patients receiving dulaglutide in the AWARD clinical trial programme, compared with higher rates observed with some other agents

But researchers are getting closer to understanding the variables that make a difference