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Approval: 1959 Indications and Usage for Phentermine Phentermine hydrochloride is a sympathomimetic amine anorectic indicated as a short-term adjunct (a few weeks) in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity for patients with an initial body mass index greater than or equal to 30 kg/m2, or greater than or equal to 27 kg/m2 in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia)

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The OS rate at 10 years was 55% for the ADT-plus-radiation therapy group versus 49% for the ADT-alone group

Microglial activation parallels system degeneration in multiple system atrophy