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This means post-thyroidectomy patients on semaglutide may require monitoring of TSH levels and potential adjustments to thyroid replacement dosing to maintain optimal hormone levels

Despite notable methodological advantages, oral GLP-1 agonist research continues to encounter unresolved mechanistic and translational challenges

Critical long-term safety evaluation Numerous critical safety factors need consideration in the selection of patients

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For some patients, the next step may be another medication, a structured medical weight-loss plan, or a non-surgical option such as the Allurion Smart Capsule, also known as the swallowable gastric balloon