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Description
Consequently, GLP-1 that is secreted by intestinal L-cells is rapidly degraded by dipeptylpeptidase-4 (DPP-4) in the endothelium of the portal circulation and in the liver, as well as by a soluble circulating moiety of DPP-4
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In addition, we showed that GLP-1 and GLP-1R co-localized with various endosomal markers and adenylate cyclase in the alpha cells of diabetic rats
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