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Description
Zepbound treatment follows a structured dose escalation protocol designed to optimize weight loss while minimizing adverse effects
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All prescriptions are written based on physician discretion following medical guidelines

Overall, intentional weight loss in older adults appears safe, and may provide benefit to physical function, disability, QoL and cardiometabolic outcomes, when done under supervision of clinicians
The goal is not simply eating as little as possible

Indeed, the common hepatic branch, as well as celiac and gastric branches, have all been implicated in contributing to the glucoregulatory effects of gut GLP-1 62,125,126 , although selective knockdown of GLP-1R in nodose ganglia does not impair oral glucose tolerance or glucose-stimulated insulin secretion, similar to genetic knockout of GLP-1R in vagal neurons 127,128
