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The Surprising Link Between GLP-1 and Mood It might seem strange, but the same medications helping people manage weight and diabetes could also be influencing mood

During significant weight loss, the fat cells beneath the skin shrink dramatically, but the overlying skin may have lost too much elasticity to contract fully

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Some patients unintentionally eat far too little

2019;30(987996):e986

Patients should be aware that severe or progressive cold intolerance especially when accompanied by significant fatigue, constipation, dry skin, hair loss, or unexplained weight gain despite continued GLP-1 therapywarrants investigation for hypothyroidism or other conditions
