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The first-line treatment for BED is cognitive behavioral therapy (CBT), which helps to identify and challenge dysfunctional thought and behavior patterns

Beyond its ability to increase the intracellular pool of Ca 2+ , GLP-1 also affects insulin secretion via cAMP-mediated regulation of exocytosis (Figure 6)

The animals were weighed and handled daily from day 3

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Kelly AS, Auerbach P, Barrientos-Perez M, Gies I, Hale PM, Marcus C, Mastrandrea LD, Prabhu N, Arslanian S NN8022-4180 Trial Investigators