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It can affect multiple organ systems, including respiratory, cardiovascular, neurological, musculoskeletal and immunological, with the constellation of more than 200 possible symptoms varying from person to person and commonly including debilitating fatigue

The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis

Behavioral interventions have shown modest weight loss but are difficult to maintain

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It is the same active ingredient but not the same product

In a prospective open-label pilot study by Krajnc et al., patients had chronic IIH under treatment (some had persistent papilledema ~ 70% at baseline) [27]