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Discuss DPP-4 inhibitors' role as add-on therapy in patients with type 2 diabetes
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Gao L, Lee BW, Chawla M, Kim J, Huo L, Du L, et al
The administration of DPP-4 inhibitors leads to a 2-3-fold elevation of endogenous GLP-1 concentration (9)
Structure-activity studies of glucagon-like peptide-1
Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg and gradually titrated upward (5 mg, 7.5 mg, 10 mg, 12.5 mg, to a maximum of 15 mg) based on therapeutic response and tolerability
