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doi:10.1155/2013/479505 Wang Y, Alkhalidy H, Liu D

However, human experiments have not proven more than a modest effect on energy expenditure, not achieving clinical significance [28]

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The FDA approved it for type 2 diabetes management in 2022 and for weight control in November 2023

N Engl J Med 375:311322 Ahrn B, Masmiquel L, Kumar H, Sargin M, Karsbl JD, Jacobsen SH, Chow F (2017) Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): a 56-week, double-blind, phase 3a, randomised trial

[DOI] [PubMed] [Google Scholar] 343.Persson K., Gingerich R.L., Nayak S., Wada K., Wada E., Ahren B