bodybuilding and glp 1 GLP-1 agonists in weight management: moral and philosophical implications 442: GLP-1 | A Closer
Description
It showed studies having semaglutide drug as intervention showed significant heterogeneity among each other with the ones having tirzepatide showed negligible heterogeneity between each other

Morris JK, Bomhoff GL, Gorres BK, Davis VA, Kim J, Lee PP, et al

DPP-4=dipeptidyl peptidase-4

Diabetes Obes Metab 25(7):19321941
[34] [35] In the brain, they act on satiety centers to reduce appetite and food intake

However, they work through different mechanisms and are often considered less effective than the newer GLP-1 agonists for significant weight loss