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With GLP-1 receptor agonists netting manufacturers more than $10 billion per year in the US alone and with sales expected to rise in the coming decade, 6 every additional year of brand-name market exclusivity may be associated with hundreds of millions of dollars in manufacturer revenue

Recent guidance recommends individualized perioperative plans potentially holding doses before elective surgery

The focus has been on the development of pre-operative and pre-procedural guidelines not on the impact of GLP-1s on IBS or sensitive guts

These adverse events lead some patients to discontinue therapy before achieving optimal clinical outcomes, reducing long-term treatment adherence

As the obesity epidemic fuels demand for these new drugs, Lilly looks set to retain its lead, unless a competitor can outpace its innovation and commercialization in the GLP-1 field

Follow her @ByJessBartlett.