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[12] [13] Readers should note that direct head-to-head comparisons with GLP-1 monotherapy agents have not been conducted

Chronic stress can disrupt appetite regulation in the brain: Our brains are designed to receive hunger and satiety cues from the body and our environment, like a grumbling stomach or low blood sugar levels

Research published in major obesity journals documents this behavioral change as one of the medication's most powerful mechanismspatients aren't white-knuckling their way through cravings

Traditional dieting can't fix a signaling problem

Its potential to aid in weight reduction can be crucial for those with weight loss goals

2025, doi: 10.1016/j.ajcnut.2025.04.023