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SURPASS-CVOT: The Effect of Tirzepatide Versus Dulaglutide on Major Adverse Cardiovascular Events in Patients With Type 2 Diabetes

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However, tirzepatide may lead to fewer or less severe nausea symptoms compared to semaglutide, according to studies conducted by independent researchers, such as Phase 3 randomized controlled trials (RCTs) found in PubMed's electronic databases

J Endocrinol (2014) 221:T3141

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So your choice will also come down to the daily pill versus the weekly injection, and what the price differences are there