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Sensitivity analyses using wider margins demonstrated consistent relative patterns, supporting the robustness of the findings

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The alpha level for the interim analysis was to be calculated based on the fraction of 133 planned primary MACE-4 outcomes available at the interim analysis, with gamma of 6.6 guided by the HwangShihDe Cani method 43

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Many commercial plans cover evaluation and management visits coded with obesity diagnoses (E66.01, E66.09), metabolic testing, and laboratory work

Sleep Latency, which is how long it takes you to fall asleep each night
