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Instead of stopping medication suddenly, some people may transition gradually to lower doses

2024;59:S52S75

Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE): a phase 3b, double-blind, randomised, placebo-controlled trial

This approach might suit patients with a stable or satisfactory response, good tolerability and no pressing safety, access, or cost concerns

The primary circadian clock, located in the suprachiasmatic nucleus of the hypothalamus coordinates various brain areas and peripheral tissues throughout the body via neural and hormonal signals 32