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This makes sense because both drugs act through GLP-1 receptor pathways, and GI effects are inherent to that mechanism

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Clinical evidence demonstrates that GLP-1 medications continue to provide metabolic benefits, including improved glycaemic control and, in people with type 2 diabetes, cardiovascular risk reduction, even when weight loss stabilises

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41,42 In humans, heart rate increases following a meal, mediated by withdrawal of parasympathetic modulation of the heart (assessed by diminished HRV) and not by sympathetic activation

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As of July 2024, we found 3 studies recruiting participants for addiction-related conditions

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Diabetologia2005 Oct;48(10):2170-8

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The gradual weight loss produced by semaglutide (versus crash dieting) naturally supports better muscle preservation

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