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This makes sense because both drugs act through GLP-1 receptor pathways, and GI effects are inherent to that mechanism

Clinical evidence demonstrates that GLP-1 medications continue to provide metabolic benefits, including improved glycaemic control and, in people with type 2 diabetes, cardiovascular risk reduction, even when weight loss stabilises

41,42 In humans, heart rate increases following a meal, mediated by withdrawal of parasympathetic modulation of the heart (assessed by diminished HRV) and not by sympathetic activation

As of July 2024, we found 3 studies recruiting participants for addiction-related conditions

Diabetologia2005 Oct;48(10):2170-8

The gradual weight loss produced by semaglutide (versus crash dieting) naturally supports better muscle preservation
