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MHRA defines medicinal products as substances that prevent or treat disease, or modify physiological function

Gillespie et al

Older patients have stiffer arteries, more blockages in their arteries and may get much more symptomatic from a change in blood pressure

Severe gastrointestinal symptoms during semaglutide treatment, including persistent nausea, vomiting, or diarrhea, warrant medical consultation, particularly in anticoagulated patients

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Similarly, in a pooled analysis of results with semaglutide, a significant improvement was found in the annual impairment of eGFR, which was particularly pronounced in those with a baseline eGFR between 30 and 60 ml/min., but which remained significant in those with a higher baseline eGFR [30]