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Katie Jones is a registered nurse and certified IV therapy specialist based in Temecula, California

Age, body weight, baseline metabolism, and stomach sensitivity all contribute to side-effect timing and intensity

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Step 2: Weekly Weight Loss Injections Quick once-a-week injections with dosing that gradually increases over time to allow your body to comfortably adjust to the medication

With manufacturer coupons and discounts, costs can be lowered to $7000 to $8000/year [[72], [73], [74]]

References (this section): NEJM (2023): Phase 2 trial publication Eli Lilly: Phase 2 results (mentions 24.2% at 48 weeks as a secondary endpoint) Eli Lilly (Dec 2025): Phase 3 TRIUMPH-4 topline results announcement Retatrutide side effects: what trials report (not medical advice) Searches like retatrutide side effects and side effects of retatrutide usually refer to events reported in clinical trial publications and sponsor summaries