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A comparative study conducted between GLP-1RA + Metformin in contrast to cyproterone acetate/ethinylestradiol + Metformin in overweight PCOS women, conducted over a period of 12 weeks, implied that GLP-1 RA+Metformin was superior in reducing the waist circumferences as well as preserving blood sugar levels by improved HbA1c levels and regulating menstrual cycle

Role of MR in elucidating causal effects The GM can affect and interact with host health in numerous ways, and the arrow of causality is often bidirectional or even multidirectional

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Fermented foods such as kefir, sauerkraut, and kimchi are good sources of probiotics

The trials on GLP-1s are very compelling on weight and CVD outcomes, but I'm increasingly skeptical of the observational literature on this topic--not only because of the limitations of EHR and claims data and the potential for selective reporting, but also because those data sources are doing a poor job of capturing what people are actually doing