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He later described exendin-4 as the fifth child of our familya creation he nurtured despite all evidence that the world was not interested

Important safety considerations include contraindications in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, caution in those with a history of pancreatitis, increased risk of gallbladder disease, potential for acute kidney injury with dehydration, and possible worsening of diabetic retinopathy with rapid glycemic improvement

Until Phase 3 data with rigorous body composition analysis and long-term safety monitoring are available, semaglutide remains the proven standard by a wide margin

Moreover, Semaglutide GLP-1 and Liraglutide have been shown to have beneficial effects on cardiovascular risk factors

This was not a task she relished

10.1038/sj.ijo.0803001 143
