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While the anti-aging implications have not been studied directly in humans, the mechanistic pathway is well-established and suggests potential benefits for anti-aging applications

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[DOI] [PubMed] [Google Scholar] 92.Wharton S., Lau D.C.W., Vallis M., Sharma A.M., Biertho L., Campbell-Scherer D., Adamo K., Alberga A., Bell R., Boule N., et al

Substantial improvement in beta-cell function with initial combination therapy of sitagliptin and metformin in patients with type 2 diabetes after 1 year of treatment