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an investigational combination therapy being developed by Novo Nordisk that merges two powerful agents: (1) a long-acting amylin analog with a sequence to make it a calcitonin receptor agonist (2) a blockbuster GLP-1 receptor agonist ?via complementary hormonal pathways: mimics the natural hormone amylin, which is co-secreted with insulin

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Using an integrated ligand and structure-based virtual screening pipeline, explicitly combining complementary ligand-based descriptors, multi-fingerprint similarity, electrostatic similarity, pharmacophore modeling, and multi-conformation docking under a consensus-driven selection strategy, we were able to identify three chemically distinct classes of GLP-1R agonist candidates: GQB47810, a non-peptidic molecule

As a GP, I see that attention show up in the way people come to talk about their health