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Water alone is adequate for hydration, and a balanced diet is sufficient to regulate electrolyte levels

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Clinical trials demonstrate that combining GLP-1 receptor agonists with insulin leads to greater A1C reductions than either drug alone

Semaglutide is a GLP-1 receptor agonist, originally developed for type 2 diabetes and now FDA-approved for chronic weight management

Semaglutide was sent into clinical trials in June 2018, and STEP 1 was completed in March 2021

The Patient Reality It is easy, in an analysis this focused on structural economics and competitive strategy, to lose sight of what the PBM opacity debate means for the 131 million Americans who take at least one prescription drug regularly