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eBioMedicine DOI:10.1016/j.ebiom.2025.106119 Abstract Tirzepatide reduces alcohol drinking and relapse-like behaviours in rodents Background Alcohol use disorder (AUD) remains a major public health problem, with few effective medications currently available

However, safety depends on proper sourcing, dosing, and administration

Consider running retatrutide as monotherapy at its full dose range first, as the triple agonist alone produces excellent results

Staying hydrated while drinking alcohol, limiting alcohol consumption, and avoiding smoking are some ways to help prevent getting a sore throat after drinking