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However, availability of cost-effective biosimilars of semaglutide starting 2026 is likely to influence patient perception of the drug in a price-sensitive Chinese market, especially for obese patients in the absence of reimbursement for weight loss drugs

Serious adverse events including pancreatitis and gallbladder disease have been reported at lower rates across clinical trial populations

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Though not recommended explicitly for acute bipolar depression, these agents are often initiated alongside first-line agents as they have a good safety and efficacy record for depressive prophylaxis