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Description
Overweight with a body mass index (BMI) 27 kg/m2 or higher and at least one weight-related health condition, such as high blood pressure, high cholesterol, or high blood sugar
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The phosphorylated JAKs, especially JAK2, in turn stimulates the phosphorylation of three residues on the intracellular domain of LepRb (Tyr985, Tyr1077 and Tyr1138), and recruits distinct downstream signaling molecules to a leptin-specific signaling pathway to exhibit diverse physiological functions [84, 86]
Alkas J, Bosi A, Sjolander A, Barany P, Elinder CG, Fu EL
It's usually mild
Importantly, the Jiang et al
