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described the activation of mammalian target of rapamycin (mTOR) as a crucial pathway for neuron protection, and that GLP-1RA affects mTOR activity by reducing caspase-3 and caspase-8 (51)
Biochem Biophys Res Commun 472(1):201208 Read NW, McFarlane A, Kinsman RI, Bates TE, Blackhall NW, Farrar GB et al (1984) Effect of infusion of nutrient solutions into the ileum on gastrointestinal transit and plasma levels of neurotensin and enteroglucagon

Importantly, the metabolic and behavioral abnormalities observed in male BBS5 / mice were recapitulated in females (Supplemental Figure 1, DJ), suggesting that there were no sex differences in disease manifestation

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