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Tirzepatide (Mounjaro for diabetes, Zepbound for weight management) is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, not a pure GLP-1 medication

To counteract potential protopathic or ascertainment bias, any instances of primary and secondary outcomes that manifested before the designated index date were disregarded, prompting a repeat of the PSM process

Testosterone effects are not yet apparent as blood levels are still building

Diabetes Metab J 2024;48(2):196e207

Treatment often starts with a low dose that is slowly increased over several weeks

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