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Then, the proprotein convertase Furin recognizes and cleaves a specific sequence in Pro-GDF-8 to form Latent GDF-8, a key step in GDF-8 maturation

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This decrease in PRV did not appear to be linear, instead it leveled off after the third component, with no significant difference in PRV between the MetS and DM populations

Given the high prevalence of psychiatric comorbidities, structured screening using tools like the Patient Health Questionnaire-9 (PHQ-9) or Binge Eating Scale (BES) is recommended