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A review of the pharmacotherapy of obesity: GLP-1 receptor agonists

40 Nevertheless, accumulating evidence indicates that CR is detrimental to skeletal metabolism, as evidenced by reductions in BMD and bone mineral content (BMC), diminished bone formation indices (e.g., bone formation rate, osteoblast number), and a concomitant increase in bone resorption

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Evolus has since submitted the final module of its Premarket Approval application to the FDA

Prioritize sleep and stress regulation, and keep hydration and fiber consistent

An alternative starting protocol uses 1mg for the first four weeks before moving to 2mg, then following the standard escalation from there