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These may include nausea, early satiety, bloating, reflux symptoms, constipation, or diarrhoea, particularly during the initial stages of treatment or after dose increases

BMJ Open Ophthalmol

The slower titration protocols being used in Phase 3 trials may further reduce discontinuation rates by allowing more gradual adaptation

[DOI] [PubMed] [Google Scholar] [214].Smart AL, Gaisford S, Basit AW, Oral peptide and protein delivery: intestinal obstacles and commercial prospects, Expert Opin Drug Deliv, 11 (2014) 13231335

[DOI] [PubMed] [Google Scholar] 2.Wei S., Wang L., Evans P.C., Xu S

That said, each medical weight loss option has pros and cons depending on what your goals and medical history are, so its important to talk to a healthcare professional