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Some studies have linked the popular weight-loss drugs with a potentially higher risk of eye problems and vision loss

PMID: 32282828

Eriocitrin inhibits the proliferation of liver cancer cells by arresting the cell cycle in the S phase by upregulating p53, cyclin A, cyclin D3 and CDK6

FDA approved for type 2 diabetes, not approved for weight loss, though doctors may prescribe off-label.A higher-dose semaglutide (Wegovy) is FDA approved for chronic weight management.Both are manufactured by Novo Nordisk Mounjaro and Zepbound are the same drug called tirzepatide works as a dual GIP and GLP-1 receptor agonist.But FDA-approved for different conditions: Mounjaro for Type 2 Diabetes, and Zepbound for chronic weight management and Obstructive Sleep Apnea.Both are manufactured by Eli Lilly.

Conclusion GLP-1RAs show significant promise as a potential disease-modifying therapy for neurodegenerative and inflammatory eye diseases, acting through both systemic metabolic improvements and direct ocular mechanisms, representing a paradigm shift beyond their metabolic indications.

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