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Overall, the addition of oral semaglutide 7 mg or 14 mg compared favorably to the addition of sitagliptin 100 mg in patients with T2DM inadequately controlled on metformin sulfonylurea background therapy

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There is evidence that GLP-1 agonists have direct effects on the brain, including an ability to restore dopamine imbalance, Roger McIntyre, a professor of psychiatry and pharmacology at the University of Toronto, told Psychiatric News in December 2023