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Finally, a 26-week, double-blind trial evaluated the efficacy and safety of ertugliflozin in T2DM patients who were inadequately controlled (HbA1c, 7.010.5%) after a minimum of 8 weeks of metformin therapy ( 1500 mg/day) [55]

Injection site reactions : Monitoring for local reactions, proper injection technique education, and site rotation

Red flag symptoms requiring urgent GP consultation include abnormal vaginal bleeding, severe vulval pain or fissuring, pelvic pain, fever, spreading cellulitis, severe balanitis, difficulty retracting the foreskin with pain and swelling (possible paraphimosis), or symptoms that do not resolve with standard antifungal treatment

"Escalating should not be a race to the maximum tolerated dose," Kaplan said

An expanded portfolio of multi-agonists would allow physicians to tailor therapy that targets specific facets of metabolic disease
Across the 39 companies we reviewed, 87% offered structured wrap-around support, including one or more of the following: Tracking and goal-setting tools Meal plans and recipes Nutrition counseling Behavioral health tools Virtual support groups or community chat Virtual workouts and exercise plans Lab monitoring 4
