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Bottom line Tirzepatide nausea is common, but that doesnt make the discomfort any easier

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Skipping titration increases the likelihood of severe nausea, vomiting, prolonged diarrhea , and potentially dangerous dehydration

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Every single dose is administered on top of a higher residual drug concentration than weekly dosing would produce

Side Effects Nausea is the most common side effect of both medications, often occurring shortly after a first-time dose or dose increase