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However, emerging reports and legal filings have linked the use of GLP-1 receptor agonists to an increased risk of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE). While the drugs themselves are not blood thinners or thickeners in the traditional sense, the physiological changes they trigger in the body can create a "perfect storm" for clot formation
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The results of the Evaluation of LIXisenatide in Acute coronary syndrome (ELIXA) trial, the first cardiovascular outcomes trial for the short-acting GLP-1 RA lixisenatide, were also published recently [52]
J Am Chem Soc
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2020), which could contribute to diabetic cystopathy
