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How GLP-1 Medications Work and Why Discontinuation Matters GLP-1 receptor agonists like semaglutide function by increasing feelings of fullness, slowing stomach emptying, and reducing appetite-driven eating patterns

Often dubbed the 'triple-G' or 'Godzilla' of weight loss, it targets three different hormone receptors to dramatically suppress appetite and increase fat burning, while current medications like Wegovy and Mounjaro target one or two

le Roux, C

2004;287:E120915

TSH (thyroid-stimulating hormone): Hypothyroidism can mimic or worsen weight gain

Semaglutide (Wegovy, Ozempic) Semaglutide injections are usually the least expensive option and is effective for many patients