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GLP-1 also induces a rapid cAMP-dependent activation of extracellular signaling kinase, ERK1/2, and a delayed -arrestin [an adaptor protein necessary for GLP-1r signaling (216)]-dependent increase of ERK1/2 signaling (186)

118 It has been shown to improve comorbidities like T2DM, dyslipidemia, sleep apnea, and hypertension and reduce cardiovascular risk

Tariq says

Research suggests GLP-1 receptors may be present in taste buds and throughout the gastrointestinal tract, though this evidence is primarily from preclinical studies

Journal of Diabetes Investigations

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